Bioprosthesis Leaflet Thrombosis Following Self-Expanding Valve-in-Valve Transcatheter Aortic Valve Replacement in Patient Taking Factor Xa Inihibitor and Warfarin: A Case Report

An 87year-old female with symptomatic severe aortic stenosis underwent transcatheter valve replacement (TAVR) via the transfemoral approach with a 29mm self-expanding device. Moderate to severe paravalvular regurgitation led to the development of congestive heart failure and hospital readmission one month following TAVR. A second 29mm valve was placed to abolish the paravalvular regurgitation. Routine follow-up computed tomography (CT) imaging demonstrated leaflet thickening and decreased leaflet mobility suggesting valve thrombosis, despite adherence to Factor Xa inhibitor.
Source: Cardiovascular Revascularization Medicine - Category: Cardiology Authors: Source Type: research