High doses of recombinant mannan ‐binding lectin inhibit the binding of influenza A(H1N1)pdm09 virus with cells expressing DC‐SIGN

This study demonstrates that high doses of MBL can inhibit binding of influenza A(H1N1)pdm09 virus to DC‐SIGN‐expressing cells in the presence of complement. Our results suggest that DC‐SIGN may be an alternative receptor for influenza A(H1N1)pdm09 virus.

Source: APMIS - May 11, 2017 Category: Research Authors: Lei Yu, Shiqiang Shang, Ran Tao, Caiyun Wang, Li Zhang, Hao Peng, Yinghu Chen Tags: Original Article Source Type: research