Dickkopf-3 Ablation Attenuates the Development of Atherosclerosis in ApoE-Deficient Mice [Valvular Heart Disease]

ConclusionsDKK3 expression in macrophages is involved in the pathogenesis of atherosclerosis through modulation of inflammation and inactivation of the Wnt/β‐catenin pathway.

Source: JAHA:Journal of the American Heart Association - February 20, 2017 Category: Cardiology Authors: Cheng, W.-L., Yang, Y., Zhang, X.-J., Guo, J., Gong, J., Gong, F.-H., She, Z.-G., Huang, Z., Xia, H., Li, H. Tags: Atherosclerosis, Vascular Disease Original Research Source Type: research