Clinical Outcomes of Remote Ischemic Preconditioning Prior to Cardiac Surgery: A Meta–Analysis of Randomized Controlled Trials [Systematic Review and Meta-Analysis]

ConclusionsRIPC does not reduce morbidity or mortality in patients undergoing cardiac surgery with cardiopulmonary bypass. In the subgroup of studies in which propofol was not used, a reduction in AKI was seen, suggesting that propofol may interact with the protective effects of RIPC. Future studies should evaluate RIPC in the absence of propofol anesthesia.

Source: JAHA:Journal of the American Heart Association - February 20, 2017 Category: Cardiology Authors: Pierce, B., Bole, I., Patel, V., Brown, D. L. Tags: Cardiovascular Surgery, Meta Analysis Systematic Review and Meta ‐ Source Type: research