CCR7-CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia [Health Services and Outcomes Research]

ConclusionsThese data show that CCR7‐CCL19/CCL21 axis facilitates retention CD4+ T lymphocytes at the site of collateral artery remodeling, which is essential for effective arteriogenesis.

Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Nossent, A. Y., Bastiaansen, A. J. N. M., Peters, E. A. B., de Vries, M. R., Aref, Z., Welten, S. M. J., de Jager, S. C. A., van der Pouw Kraan, T. C. T. M., Quax, P. H. A. Tags: Angiogenesis, Peripheral Vascular Disease Original Research Source Type: research