Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study [Coronary Heart Disease]

BackgroundPlaque rupture and erosion are the 2 most common mechanisms for acute coronary syndromes. However, the outcome of these 2 distinct pathologies in patients with acute coronary syndromes has never been studied.Methods and ResultsWe retrospectively studied 141 patients with acute coronary syndromes who underwent optical coherence tomography (OCT) imaging of the culprit lesion prior to stenting from the Massachusetts General Hospital OCT Registry. Management (stent versus no stent), poststent OCT findings, and outcomes were compared. Among the 141 culprit lesions, rupture was found in 79 (56%) patients and erosion in 62 (44%). Stent implantation was performed in 77 (97.5%) patients with rupture versus 49 (79.0%) in those with erosion (P

Source: JAHA:Journal of the American Heart Association - February 24, 2017 Category: Cardiology Authors: Hu, S., Zhu, Y., Zhang, Y., Dai, J., Li, L., Dauerman, H., Soeda, T., Wang, Z., Lee, H., Wang, C., Zhe, C., Wang, Y., Zheng, G., Zhang, S., Jia, H., Yu, B., Jang, I.-K. Tags: Optical Coherence Tomography (OCT), Treatment, Thrombosis Original Research Source Type: research