Mesial temporal lobe epilepsy diminishes functional connectivity during emotion perception

Mesial temporal lobe epilepsy (MTLE) is the most prevalent form of refractory epilepsy in adults, and is now considered as a complex network disease that affects widely distributed brain regions organized in networks in the afflicted hemisphere (Berg et al., 2010 and Jokeit et al., 1997). Consistent with structural and functional abnormalities extending far beyond the mesial temporal lobe (Bernhardt et al., 2013), deficits in neuropsychological functions relying on large-scale networks such as memory (Bell et al., 2011), language (Bartha-Doering and Trinka, 2014) and executive functions (Stretton and Thompson, 2012) are a common characteristic of MTLE.

Source: Epilepsy Research - May 9, 2017 Category: Neurology Authors: Bettina K. Steiger, Angela M. Muller, Esther Spirig, Gianina Toller, Hennric Jokeit Source Type: research