Resting State Functional Connectivity in Primary Insomnia, Generalized Anxiety Disorder and Controls

Sleep abnormalities are extremely common in anxiety disorders and may contribute to their development and persistence. Their shared pathophysiological mechanisms could thus serve as biomarkers or targets for novel therapeutics. Individuals with Primary Insomnia were age- and sex-matched to controls and to persons with Generalized Anxiety Disorder. All underwent fMRI resting-state scans at 3-T. In Primary Insomnia and controls, sleep was recorded for 2 weeks using diaries and actigraphy. All participants completed state-anxiety and neuroticism inventories.

Source: Psychiatry Research: Neuroimaging - May 8, 2017 Category: Psychiatry Authors: Edward F. Pace-Schott, Jared P. Zimmerman, Ryan M. Bottary, Erik G. Lee, Mohammed R. Milad, Joan A. Camprodon Source Type: research