Post-transfusion Hypertension and Seizure in Congenital Hemolytic anemia: A Case Report and Literature Review

We report this syndrome in a 12-year-old Malay girl with hemoglobin E-beta-thalassemia, who underwent intensive transfusion and subsequently had headache, visual loss, severe hypertension and seizures. A comprehensive literature review revealed 30 patients with this syndrome, of whom 15 had intracranial bleed and 12 among these 15 died. A less-intensive transfusion regimen among patients with chronic hemolytic anemia and prompt detection and management of hypertension may prevent this potentially fatal syndrome.
Source: Journal of Tropical Pediatrics - Category: Tropical Medicine Authors: Tags: Brief Reports Source Type: research