Exploring Evolutionary Relationships Across the Genome Using Topology Weighting [Population and Evolutionary Genetics]

We describe our method for topology weighting by iterative sampling of subtrees (Twisst), and test it on both simulated and real genomic data. Overall, we show that this is an informative and versatile approach, suitable for exploring relationships in almost any genomic dataset. Scripts to implement the method described are available at http://github.com/simonhmartin/twisst.

Source: Genetics - May 5, 2017 Category: Genetics & Stem Cells Authors: Martin, S. H., Van Belleghem, S. M. Tags: Population and Evolutionary Genetics Source Type: research