Sex differences and the role of sex hormones in stress reactivity, emotion regulation and craving in drug and alcohol dependence

Aims: Sex hormones are known to modulate the subjective effects of drugs. In three studies, we examined the effects of progesterone and its neuroactive derivative allopregnanolone (ALLO) on emotional and cognitive regulation, stress response, and craving in cocaine and alcohol dependent (CAD) patients. Methods: STUDY 1: The Mayer, Salovey, and Caruso Emotional Intelligence Test (MSCEIT) was administered to 98 CAD (55 M/43 F) and 56 healthy (28 M/28 F) individuals. Performance was also assessed by menstrual cycle in the women.
Source: Alcohol - Category: Addiction Authors: Source Type: research