Gender differences in alcohol-induced immune response in human and animal adolescents with binge drinking: Role of TLR4

Adolescent stress response and coping strategies differ to that of adults. Heavy binge drinking in adolescence is the most frequent pattern of drinking among teenagers. Experimental evidence indicates the participation of the immune system and TLR4 response in the ethanol-induced adolescent brain damage and the vulnerability of the female vs males. We assess the plasma cytokine and chemokine levels in male and female adolescents during acute alcohol intoxication, and correlate these results with the TLR4 response.

Source: Alcohol - May 1, 2017 Category: Addiction Authors: Mar ía Pascual, Jorge Montesinos, Miguel Marcos, Francisco-Javier Laso, Consuelo Guerri Source Type: research