Noninvasive imaging systems for gametes and embryo selection in IVF programs: a review

Summary Optimizing the efficiency of the in vitro fertilization procedure by improving pregnancy rates and reducing the risks of multiple pregnancies simultaneously are the primary goals of the current assisted reproductive technology program. With the move to single embryo transfers, the need for more cost‐effective and noninvasive methods for embryo selection prior to transfer is paramount. These aims require advancement in a more acquire gametes/embryo testing and selection procedures using high‐tech devices. Therefore, the aim of the present review is to evaluate the efficacy of noninvasive imaging systems in the current literatures, focusing on the potential clinical application in infertile patients undergoing assisted reproductive technology treatments. In this regards, three advanced imaging systems of motile sperm organelle morphology examination, polarization microscopy and time‐lapse monitoring for the best selection of the gametes and preimplantation embryos are introduced in full. Lay description In assisted reproductive technology (ART) programs, the main goal is improving pregnancy rates and reducing the risks of multiple pregnancies simultaneously in infertile patients. So, more cost‐ effective and noninvasive methods for selecting gametes before the in vitro fertilization (IVF), and embryos before transfer to uterine are unavoidable. In this regard, advancement in a more acquires gametes/embryo testing and selection procedures need high tech devices....
Source: Journal of Microscopy - Category: Laboratory Medicine Authors: Tags: Review Article Source Type: research