Leptomeningeal Enhancement at 7T in Multiple Sclerosis: Frequency, Morphology, and Relationship to Cortical Volume

CONCLUSIONSLeptomeningeal enhancement on postcontrast 7T MPFLAIR is more prevalent than prior reports at 3T—occurring at frequencies closer to histopathologic data. Spread/fill foci are associated with reduced cortical gray matter volumes and may represent blood‐meningeal barrier breakdown near sites of meningeal inflammation, whereas nodular foci may be a normal variant.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fjon.12444

Source: Journal of Neuroimaging - March 1, 2017 Category: Radiology Authors: Daniel M. Harrison, Kevin Y. Wang, Julie Fiol, Kerry Naunton, Walter Royal, Jun Hua, Izlem Izbudak Tags: Clinical Investigative Study Source Type: research