Obesity increases the risk of end-stage renal disease among living kidney donors

This study looked at the risk of ESRD associated with obesity at the time of donation among 119 769 live kidney donors in the United States with a maximum follow-up was 20 years. The estimated risk of ESRD 20 years after donation was 93.9 per 10 000 for obese; significantly greater than the 39.7 per 10 000 for non-obese live kidney donors. When adjusted for age, sex, ethnicity, blood pressure, baseline estimated glomerular filtration rate, and relationship to recipient, obese live kidney donors had a significant 86% increased risk of ESRD compared to their non-obese counterparts (adjusted hazard ratio 1.86; 95% confidence interval 1.05–3.30). Furthermore, for each unit increase in BMI above 27 kg/m2 there was an associated significant 7% increase in ESRD risk (1.07, 1.02–1.12).           : Body Mass Index in 1.2 Million Adolescents and Risk for End-Stage Renal Disease Risk of End-Stage Renal Disease Following Live Kidney Donation Acute dialysis risk in living kidney donors
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Chronic Kidney Disease General Nephrology Renal Transplantation Source Type: research