Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury

In conclusion, hyperoxia-induced alveolar growth impairment is mediated, in part, by ER stress. Early caffeine treatment protects developing lungs from hyperoxia-induced injury by attenuating ER stress.

Source: AJP: Lung Cellular and Molecular Physiology - May 1, 2017 Category: Respiratory Medicine Authors: Teng, R.-J., Jing, X., Michalkiewicz, T., Afolayan, A. J., Wu, T.-J., Konduri, G. G. Tags: RESEARCH ARTICLE Source Type: research