ERBB signaling attenuates proinflammatory activation of nonclassical monocytes

This study identified a novel role of neuregulin-1 (NRG-1)/ERBB signaling in the control of proinflammatory activation of monocytes. These results further improve our fundamental understanding of cardioprotective effects of NRG-1 in patients with heart failure.

Source: AJP: Heart and Circulatory Physiology - May 1, 2017 Category: Cardiology Authors: Ryzhov, S., Matafonov, A., Galindo, C. L., Zhang, Q., Tran, T.-L., Lenihan, D. J., Lenneman, C. G., Feoktistov, I., Sawyer, D. B. Tags: RESEARCH ARTICLE Source Type: research