Short-term regular aerobic exercise reduces oxidative stress produced by acute in the adipose microvasculature

In conclusion, aerobic exercise prevents high pressure-induced vascular dysfunction through an improved redox environment in the adipose microvasculature.
NEW & NOTEWORTHY We describe potential mechanisms contributing to aerobic exercise-conferred protection against high intravascular pressure. Subcutaneous adipose microvessels from exercise mice express less NADPH oxidase (NOX) II and more superoxide dismutase (SOD) and demonstrate less sensitivity to ANG II. In microvascular endothelial cells, shear stress reduced NOX II but did not influence SOD expression.

Source: AJP: Heart and Circulatory Physiology - May 1, 2017 Category: Cardiology Authors: Robinson, A. T., Fancher, I. S., Sudhahar, V., Bian, J. T., Cook, M. D., Mahmoud, A. M., Ali, M. M., Ushio-Fukai, M., Brown, M. D., Fukai, T., Phillips, S. A. Tags: RESEARCH ARTICLE Source Type: research