Population differences in Brain morphology: Need for population specific Brain template

Brain templates provide a standard anatomical platform for population based morphometric assessments. Typically, standard brain templates for such assessments are created using Caucasian brains, which may not be ideal to analyze brains from other ethnicities. To effectively demonstrate this, we compared brain morphometric differences between T1 weighted structural MRI images of 27 healthy Indian and Caucasian subjects of similar age and same sex ratio. Furthermore, a population specific brain template was created from MRI images of healthy Indian subjects and compared with standard Montreal Neurological Institute (MNI-152) template.

Source: Psychiatry Research: Neuroimaging - April 30, 2017 Category: Psychiatry Authors: Naren P Rao, Haris Jeelani, Rashmin Achalia, Garima Achalia, Arpitha Jacob, Rose dawn Bharath, Shivarama Varambally, Ganesan Venkatasubramanian, Phaneendra Yalavarthy Source Type: research