Transdiagnostic neural correlates of affective face processing in anxiety and depression

Conclusions(1) Activation in paralimbic, cingulate, and lateral prefrontal regions in response to angry faces is associated with transdiagnostic anxiety and depressive symptomatology. (2) Anxiety and depressive symptoms may exert opposing influences on lateral prefrontal activation. (3) Abnormal threat processing in GAD, SAD, and MDD may reflect shared neural dysfunction that varies with symptom load.
Source: Depression and Anxiety - Category: Psychiatry Authors: Tags: DONALD F. KLEIN AWARD FINALIST Source Type: research