A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal

This study highlights the importance of feedback mechanisms in spatiotemporal control of the stem cell niche.

Source: Molecular Systems Biology - April 28, 2017 Category: Molecular Biology Authors: Chen, K.-Y., Srinivasan, T., Tung, K.-L., Belmonte, J. M., Wang, L., Murthy, P. K. L., Choi, J., Rakhilin, N., King, S., Varanko, A. K., Witherspoon, M., Nishimura, N., Glazier, J. A., Lipkin, S. M., Bu, P., Shen, X. Tags: Quantitative Biology & Dynamical Systems, Signal Transduction, Stem Cells Articles Source Type: research