Cancer: Identifying synergistic drug combinations

Nature Reviews Drug Discovery 16, 314 (2017). doi:10.1038/nrd.2017.76 Author: Crunkhorn Sarah Drug combinations are commonly used to counter drug resistance in cancer therapy. To identify synergistic drug target combinations, Han et al. have developed a scalable CRISPR-based double-knockout system that enables parallel pairwise gene knockout. Application of this system in a chronic myeloid leukaemia (CML)
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research