Analgesia: Designing out opioid side effects

Nature Reviews Drug Discovery 16, 311 (2017). doi:10.1038/nrd.2017.68 Author: M. Teresa Villanueva Although opioids are very effective in treating pain that is associated with tissue damage and inflammation, they have important adverse effects, such as drowsiness, constipation, potential respiratory arrest and addiction. By analysing drug–opioid receptor interactions in damaged tissues, as opposed to healthy tissues, Stein and
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research