Digoxin Attenuates Murine Experimental Colitis by Downregulating Th17-related Cytokines

Conclusions: This study has shown for the first time that treatment with digoxin can ameliorate murine experimental colitis. This finding suggests that the suppression of Th17 using reagents such as digoxin could be effective in treating Crohn's disease refractory to anti–tumor necrosis factor alpha therapy.
Source: Inflammatory Bowel Diseases - Category: Gastroenterology Tags: Original Basic Science Articles Source Type: research