Context-specific roles of EMT programmes in cancer cell dissemination

Nature Cell Biology 19, 416 (2017). doi:10.1038/ncb3520 Author: M. Angela Nieto The role of the epithelial-to-mesenchymal transition in tumour progression remains a topic of intense debate. Now, data on the role of Zeb1 in the metastatic spread of pancreatic cancer clarify apparently conflicting views by revealing context-specific, differential use of individual epithelial-to-mesenchymal transition transcription factors in cancer cell dissemination.
Source: Nature Cell Biology - Category: Cytology Authors: Tags: News and Views Source Type: research