LncRNA ‐H19 Modulates Wnt/β‐catenin Signaling by Targeting Dkk4 in Hindlimb Unloaded Rat

ConclusionOur findings demonstrated that low expression of H19, induced by mechanical unloading, leads to development of DOP through inhibition of Wnt signaling by promoting Dkk4 expression.

Source: Orthopaedic Surgery - February 1, 2017 Category: Orthopaedics Authors: Bing Li, Jun Liu, Jie Zhao, Jian ‐xiong Ma, Hao‐bo Jia, Yang Zhang, Guo‐sheng Xing, Xin‐long Ma Tags: BASIC RESEARCH Source Type: research