Anaphylatoxin C5a modulates hepatic stellate cell migration

Conclusions: These data reveal that C5a regulates migration of HSC and suggest a novel mechanism by which complement contributes to hepatic fibrosis. C5a and its receptors are therefore potential therapeutic targets for the prevention and/or treatment of liver fibrosis.
Source: Fibrogenesis and Tissue Repair - Category: Biomedical Science Authors: Source Type: research