Mechanisms of central tolerance for B cells
Nature Reviews Immunology 17, 281 (2017).
doi:10.1038/nri.2017.19
Author: David Nemazee
Immune tolerance hinders the potentially destructive responses of lymphocytes to host tissues. Tolerance is regulated at the stage of immature B cell development (central tolerance) by clonal deletion, involving apoptosis, and by receptor editing, which reprogrammes the specificity of B cells through secondary recombination of
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: David Nemazee Tags: Review Source Type: research
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