Characterization of the structure, dynamics and allosteric pathways of human NPP1 in its free form and substrate-bound complex from molecular modeling

Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00095B, PaperXavier Barbeau, Patrick Mathieu, Jean-Francois Paquin, Patrick Lague The ectonucleotide phosphodiesterase/pyrophosphatase-1 (NPP1) is a type II transmembrane glycoprotein that regulates extracellular purine nucleotide and inorganic diphosphate levels through the hydrolysis of ATP into AMP and diphosphate. NPP1 is... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Molecular Biosystems - April 25, 2017 Category: Molecular Biology Authors: Xavier Barbeau Source Type: research