Reduced infectivity of waterborne viable but nonculturable Helicobacter pylori strain SS1 in mice

ConclusionsWhile other studies that have used viable, culturable SS1 via gavage or drinking water exposures to successfully infect mice, in our study, waterborne VBNC SS1 failed to colonize mice under all test conditions. Future studies could examine different H. pylori strains in similar exposure scenarios to compare the relative infectivity of the VBNC vs the viable, culturable state, which would help inform future risk assessments of H. pylori in water.

Source: Helicobacter - April 24, 2017 Category: Gastroenterology Authors: Kevin F. Boehnke, Kathryn A. Eaton, Clinton Fontaine, Rebecca Brewster, Jianfeng Wu, Joseph N.S. Eisenberg, Manuel Valdivieso, Laurence H. Baker, Chuanwu Xi Tags: ORIGINAL ARTICLE Source Type: research