Clinically Isolated Aortitis: Pitfalls, Progress, and Possibilities

Non-infectious aortitis may be caused by several distinct systemic rheumatologic diseases. In some patients, aortitis is identified either pathologically or radiologically in the absence of clinical evidence of a systemic vasculitis. By consensus nomenclature, such cases are referred to as clinically isolated aortitis (CIA). Some systemic disorders may initially present as CIA including giant cell arteritis (GCA), IgG4-related disease, infectious aortitis, and granulomatosis with polyangiitis. CIA most commonly occurs in women of European descent over the age of 50, and thus mirrors the gender, age, and geographic distribution of GCA.
Source: Cardiovascular Pathology - Category: Cardiology Authors: Source Type: research