The Effectiveness of Exercise in Adults With Systemic Lupus Erythematosus: A Systematic Review and Meta ‐Analysis to Guide Evidence‐Based Practice

Abstract BackgroundFatigue is the most common and unpleasant symptom of patients with systemic lupus erythematosus (SLE). However, there is limited information regarding how exercise affects fatigue. AimsThe purpose of this study is to review and synthesize the current knowledge concerning the effectiveness of exercise training for treating fatigue among adults with SLE. The characteristics of beneficial exercise training are further evaluated. MethodsWe conducted a systematic review and meta‐analysis. The databases searched were MEDLINE, CINAHL, PEDro, Cochrane Library, Scopus, and PQDT from their inception to February 3, 2016. The quality of each selected study was assessed using the PEDro scale. A between‐group analysis was performed to evaluate the effectiveness of the exercise training. Data were analyzed using the Cochrane Collaboration's RevMan 5.3 (Copenhagen, Denmark). ResultsTwo randomized controlled trials and one quasiexperimental study were included in this systematic review and meta‐analysis. Aerobic exercise, three times a week and of moderate intensity, was a common component of the three studies. Two studies were conducted in a supervised setting and one study was based at home. One study lasted 8 weeks and two studies lasted 12 weeks. The meta‐analysis showed that aerobic exercise could decrease fatigue (MD = –.52, 95% confidence interval [CI] [–.91, –.13], p = .009) and increase vitality (MD = 14.98, 95% CI [7.45, 22.52], p < .001). The sub...
Source: Worldviews on Evidence-Based Nursing - Category: Nursing Authors: Tags: Original Article Source Type: research