A high-protein diet during hospitalization is associated with an accelerated decrease in soluble urokinase plasminogen activator receptor levels in acutely ill elderly medical patients with SIRS

Acute illness and hospitalization in elderly individuals are often accompanied by the systemic inflammatory response syndrome (SIRS) and malnutrition, both associated with wasting and mortality. Nutritional support and resistance training were shown to increase muscle anabolism and reduce inflammation in healthy elderly. We hypothesized that nutritional support and resistance training would accelerate the resolution of inflammation in hospitalized elderly patients with SIRS. Acutely admitted patients aged>65years with SIRS were randomized to an intervention consisting of a high-protein diet (1.7g/kg/day) during hospitalization, and daily protein supplement (18.8g) and 3 weekly resistance training sessions for 12weeks after discharge (Intervention, n=14), or to standard-care (Control, n=15).
Source: Nutrition Research - Category: Nutrition Authors: Source Type: research