Sex moderates the effects of positive and negative affect on clinical pain in patients with knee osteoarthritis

Conclusions Findings suggest that men may be particularly sensitive to the effects of stable positive affect and negative affect on clinical pain. Future work with larger samples is needed in order to identify potential mechanisms driving the sex-specific effects of affect on pain. Implications The current study provides novel data that suggesting that the association of positive affect, negative affect, and pain are different in men versus women with KOA. Further understanding of the difference in affective expression between men and women may lead to the development of novel therapeutic interventions and help to identify additional modifiable factors in the prevention and management of pain.
Source: Scandinavian Journal of Pain - Category: Anesthesiology Source Type: research