Control of structure-specific endonucleases to maintain genome stability

Nature Reviews Molecular Cell Biology 18, 315 (2017). doi:10.1038/nrm.2016.177 Authors: Pierre-Marie Dehé & Pierre-Henri L. Gaillard Structure-specific endonucleases (SSEs) have key roles in DNA replication, recombination and repair, and emerging roles in transcription. These enzymes have specificity for DNA secondary structure rather than for sequence, and therefore their activity must be precisely controlled to ensure genome stability. In this Review, we
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research