Biomolecular condensates: organizers of cellular biochemistry

Nature Reviews Molecular Cell Biology 18, 285 (2017). doi:10.1038/nrm.2017.7 Authors: Salman F. Banani, Hyun O. Lee, Anthony A. Hyman & Michael K. Rosen Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes but function to concentrate proteins and nucleic acids. These condensates are involved in diverse processes, including RNA metabolism, ribosome biogenesis, the DNA damage response and signal transduction. Recent studies have shown that liquid–liquid
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research