Synchrotron X-ray diffraction to understand crystallographic texture of enamel affected by Hunter syndrome

The human enamel is a hard mineralized tissue which consists of nanorod-like hydroxyapatite crystallites which are arranged into a highly organized prism (Wu et al., 2013). At times the orientation or texture of these enamel crystallites can be affected by genetic and metabolic disorders. Hunter syndrome or Mucopolysaccharidosis II (OMIM 309900) is an X-linked lysosomal storage disorder caused by the deficiency of an enzyme known as iduronate-2-sulfatase which is required for the breakdown of glycosaminoglycans (GAGs) (Bach et al., 1973).

Source: Archives of Oral Biology - April 19, 2017 Category: Dentistry Authors: Malik Arshman Khan, Owen Addison, Alison James, Christian J. Hendriksz, Maisoon Al-Jawad Source Type: research