Paroxetine and transient ischemic attack

Use of selective serotonin reuptake inhibitors (SSRIs) is widespread, related in part to their relatively benign side‐effect profile and a good safety record, even in overdose cases. Although the SSRIs as a group are commonly used for the treatment of depression in elderly patients, the SSRI paroxetine recently was identified as a potentially inappropriate medication to be used in this population, in part because of its greater anticholinergic properties. The following study evaluated the risk of mortality associated with the use of paroxetine versus other SSRIs in elderly nursing home residents with depression.

Source: The Brown University Psychopharmacology Update - April 19, 2017 Category: Psychiatry Authors: Y. W. Francis Lam Tags: Drug ‐Drug Interactions Source Type: research