Long-term intake of a high protein diet increases liver triacylglycerol deposition pathways and hepatic signs of injury in rats

Intake of high protein (HP) diets has increased over the last years, mainly due to their popularity for body weight control. Liver is the main organ handling ingested macronutrients and it is associated with the beginning of different pathologies. We aimed to deepen our knowledge on molecular pathways affected by long-term intake of a HP diet. We performed a transcriptome analysis on liver of rats chronically fed with a casein-rich HP diet and analysed molecular parameters related to liver injury.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research