Influence of Left Atrial Function on Exercise Capacity and Left Ventricular Function in Patients With Heart Failure and Preserved Ejection Fraction [Atrial Structure and Function]

Conclusions— Cardiac magnetic resonance myocardial feature tracking–derived conduit strain is significantly impaired in HFpEF and associated with exercise intolerance. Impaired conduit function is associated with impaired early ventricular filling, as potential mechanism leading to impaired oxygen uptake. Our results propose that impaired LA conduit function represents a distinct feature of HFpEF, independent of LV stiffness and relaxation. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02459626.

http://circimaging.ahajournals.org/cgi/content/short/10/4/e005467?rss=1

Source: Circulation: Cardiovascular Imaging - March 30, 2017 Category: Radiology Authors: von Roeder, M., Rommel, K.-P., Kowallick, J. T., Blazek, S., Besler, C., Fengler, K., Lotz, J., Hasenfuss, G., Lucke, C., Gutberlet, M., Schuler, G., Schuster, A., Lurz, P. Tags: Heart Failure Atrial Structure and Function Source Type: research