Premature Ventricular Contraction Coupling Interval Variability Destabilizes Cardiac Neuronal and Electrophysiological Control: Insights From Simultaneous Cardioneural Mapping [Original Article]

Conclusions—
Variable CI PVCs affect critical populations of intrinsic cardiac nervous system neurons and alter cardiac repolarization. These changes may be critical for arrhythmogenesis and remodeling, leading to cardiomyopathy.

Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2017 Category: Cardiology Authors: Hamon, D., Rajendran, P. S., Chui, R. W., Ajijola, O. A., Irie, T., Talebi, R., Salavatian, S., Vaseghi, M., Bradfield, J. S., Armour, J. A., Ardell, J. L., Shivkumar, K. Tags: Autonomic Nervous System, Pathophysiology Original Article Source Type: research