Percutaneous Pericardial Resection: A Novel Potential Treatment for Heart Failure With Preserved Ejection Fraction [Original Articles]

Conclusions—
This proof of concept study demonstrates that pericardial resection through a minimally invasive percutaneous approach mitigates the elevation in LV filling pressures with volume loading in both normal animals and a pig model with diastolic dysfunction. Further study is warranted to determine whether this method is safe and produces similar acute and chronic hemodynamic benefits in people with heart failure and preserved ejection fraction.

Source: Circulation: Heart Failure - April 10, 2017 Category: Cardiology Authors: Borlaug, B. A., Carter, R. E., Melenovsky, V., DeSimone, C. V., Gaba, P., Killu, A., Naksuk, N., Lerman, L., Asirvatham, S. J. Tags: Hemodynamics, Pathophysiology, Heart Failure Original Articles Source Type: research