Prevalence and Clinical Implication of Double Mutations in Hypertrophic Cardiomyopathy: Revisiting the Gene-Dose Effect [Original Articles]

Conclusions—
Double mutations in patients with hypertrophic cardiomyopathy are much less common than previously estimated. With the exception of double radical MYBPC3 mutations, there is little data to guide clinical decision making in cases with double mutations.

Source: Circulation: Cardiovascular Genetics - April 18, 2017 Category: Cardiology Authors: Fourey, D., Care, M., Siminovitch, K. A., Weissler-Snir, A., Hindieh, W., Chan, R. H., Gollob, M. H., Rakowski, H., Adler, A. Tags: Genetics, Cardiomyopathy Original Articles Source Type: research