Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and Lifestyle) [Original Articles]

Conclusions— A 9p21.3 common variant seems to interact with SES to influence CAC and incident coronary events in a population-based cohort. This supports the hypothesis that better material, psychosocial, and lifestyle conditions enable higher SES groups to reduce the expression of their genetic susceptibility to coronary artery disease.
Source: Circulation: Cardiovascular Genetics - Category: Cardiology Authors: Tags: Epidemiology, Lifestyle, Genetic, Association Studies, Atherosclerosis, Coronary Artery Disease Original Articles Source Type: research