Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and Lifestyle) [Original Articles]
Conclusions—
A 9p21.3 common variant seems to interact with SES to influence CAC and incident coronary events in a population-based cohort. This supports the hypothesis that better material, psychosocial, and lifestyle conditions enable higher SES groups to reduce the expression of their genetic susceptibility to coronary artery disease.
Source: Circulation: Cardiovascular Genetics - Category: Cardiology Authors: Schmidt, B., Frolich, S., Dragano, N., Frank, M., Eisele, L., Pechlivanis, S., Forstner, A. J., Nothen, M. M., Mahabadi, A. A., Erbel, R., Moebus, S., Jockel, K.-H. Tags: Epidemiology, Lifestyle, Genetic, Association Studies, Atherosclerosis, Coronary Artery Disease Original Articles Source Type: research
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