Reference intervals for serum 24,25-dihydroxyvitamin D and the ratio with 25-hydroxyvitamin D established using a newly developed LC –MS/MS method

We describe a LC –MS/MS method to determine: 1) the relationships between serum 24,25(OH)2D and 25(OH)D; 2) serum reference intervals in healthy individuals; 3) the diagnostic accuracy of 24,25(OH)2D measurement as an indicator for vitamin D status; 4) 24,25(OH)2D cut-off value for clinically significant change be tween inadequate and sufficient 25(OH)D status.

Source: The Journal of Nutritional Biochemistry - April 13, 2017 Category: Biochemistry Authors: Jonathan C.Y. Tang, Holly Nicholls, Isabelle Piec, Christopher J. Washbourne, John J. Dutton, Sarah Jackson, Julie Greeves, William D. Fraser Source Type: research