Effect of pistachio consumption on the modulation of urinary gut microbiota-related metabolites in pre-diabetic subjects

The specific nutritional composition of nuts could affect different metabolic pathways involved in a broad range of metabolic diseases. We therefore investigated whether chronic consumption of pistachio nuts modifies the urine metabolome in pre-diabetic subjects. We designed a randomized crossover clinical trial in 39 pre-diabetic subjects. Subjects consumed a pistachio-supplemented diet (PD, 50% carbohydrates, 33% fat, including 57g/d of pistachios daily) and a control diet (CD, 55% carbohydrates, 30% fat) for 4 months each, separated by a 2-week wash-out.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research