A pilot study of esophageal motility and rikkunshito treatment for proton pump inhibitor-refractory non-erosive reflux disease: A prospective, uncontrolled, open-label trial

Conclusions In the pilot study, PPI- refractory NERD patients had with disorders of esophageal and LES motility were improved by RKT. Further studies examining esophageal motor activity of RKT in PPI-refractory NERD are required. UMIN Clinical Trial Registry identifier: UMIN000003092.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research