A Prospective, Open, Uncontrolled, Non-Randomized, Observational study of Curative Metatarsal Bone Surgery Combined With Intralesional Administration of Rh-Egf in Diabetic Neuropathic Ulceration of the Forefoot

Conclusion The combination of curative metatarsal bone surgery with intralesional administration of recombinant human epidermal growth factor resulted in a significant reduction in the re-epithelization time, recidivism and development of new diabetic lesions. The safety profile was appropriate. However, more randomized, triple blind, and placebo trials are needed to evaluate the efficacy and safety of this new therapy.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research