Orthodontic tensile strain induces angiogenesis via type IV collagen degradation by matrix metalloproteinase ‐12

ConclusionWe discovered that the orthodontic tensile strain upregulates MMP‐12 expression in the tension zone of PDL and induces angiogenesis via degradation of Col‐IV in the vascular endothelial basement membrane.

Source: Journal of Periodontal Research - April 10, 2017 Category: Dentistry Authors: T. Narimiya, S. Wada, H. Kanzaki, M. Ishikawa, A. Tsuge, Y. Yamaguchi, Y. Nakamura Tags: ORIGINAL ARTICLE Source Type: research