Electroconvulsive therapy changes the regional resting state function measured by regional homogeneity (ReHo) and amplitude of low frequency fluctuations (ALFF) in elderly major depressive disorder patients: an exploratory study

Electroconvulsive therapy (ECT) is the most effective and rapid treatment for severe major depressive disorder (MDD) in elderly patients. The mechanism of ECT is unclear, and studies on ECT in elderly MDD patients by resting-state functional magnetic resonance imaging are rare. Thirteen elderly MDD patients were scanned before and after ECT using a 3.0T MRI scanner. Regional homogeneity (ReHo) and amplitude of low-frequency fluctuations (ALFF) were processed to compare resting-state function before and after treatment.

Source: Psychiatry Research: Neuroimaging - April 7, 2017 Category: Psychiatry Authors: Xiao-ming Kong, Shu-xian Xu, Yan Sun, Ke-yong Wang, Chen Wang, Ji Zhang, Jin-xiang Xia, Li Zhang, Bai-jian Tan, Xin-hui Xie Source Type: research